FLEE Plus IGR for Cats Spot-On Treatment for Cats and Kittens effectively kills fleas and ticks (including those that may transmit Lyme disease). Contains Fipronil 9.8%, (S)-methoprene 11.8%. Includes a 3 month supply in 0.069 fl. oz. applicator. Other Takeaways Waterproof Fast-acting and long-lasting control of fleas, ticks, and chewing lice for up to one month on cats Dual Action: Fipronil with (S)-methoprene insect growth regulator effectively breaks the flea life cycle